3-Fluorophenylboronic acid → HCID 86718124, compound

Participants

Reaction Steps

The product was obtained via a Suzuki coupling reaction using the method previously shown in Example 20, Step 3, using methyl 3-chloro-2-phenylquinoxaline-6-carboxylate (90 mg, 0.30 mmol, 1.00 equiv) and 3-fluorophenylboronic acid (63.4 mg, 0.45 mmol, 1.50 equiv) as reactants. Purification via silica gel column (dichloromethane/methanol (10:1)) yielded 60 mg (55%) of 3-(3-fluorophenyl)-2-phenylquinoxaline-6-carboxylic acid as a light yellow solid.

Provenance & Evidence