HuagongsheHuagongshe Chemistry Print Report · For research reference only
Furan-3-boronic acid → HCID 86718126, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Furan-3-boronic acid | HCID 2734358 | — |
| Reactant | Methyl 3-bromo-2-phenylquinoxaline-6-carboxylate | HCID 86667202 | — |
| Product | HCID 86718126 | HCID 86718126 | 25.1% |
Reaction Steps
The product was obtained via a Suzuki coupling reaction using the method previously shown in Example 20, Step 3, using methyl 3-bromo-2-phenylquinoxaline-6-carboxylate (100 mg, 0.29 mmol, 1.00 equiv) and furan-3-yl boronic acid (48.8 mg, 0.44 mmol, 1.50 equiv) as reactants. Purification via silica gel column (dichloromethane/methanol (10:1)) yielded 23 mg (24%) of 3-(furan-3-yl)-2-phenylquinoxaline-6-carboxylic acid as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09370522B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-954dcd1eee954dd9a67a0163e64a7645 |
| Source note | uspto-grants-2016_06 |