(4-Methoxyphenyl)boronic acid → HCID 86718115, compound

Participants

Reaction Steps

The product was obtained via a Suzuki coupling reaction using the method previously shown in Example 20, Step 3, using methyl 3-bromo-2-phenylquinoxaline-6-carboxylate (150 mg, 0.44 mmol, 1.00 equiv) and 4-methoxyphenylboronic acid (100 mg, 0.66 mmol, 1.50 equiv) as reactants. Purification via silica gel column (dichloromethane/methanol (10:1)) yielded 105 mg (65%) of 3-(4-methoxyphenyl)-2-phenylquinoxaline-6-carboxylic acid as a yellow solid.

Provenance & Evidence