1,1'-Biphenyl-4-yl-boronic acid → HCID 86718130, compound

Participants

Reaction Steps

The product was obtained via a Suzuki coupling reaction using the method previously shown in Example 20, Step 3, using methyl 3-bromo-2-phenylquinoxaline-6-carboxylate (100 mg, 0.29 mmol, 1.00 equiv) and 4-phenyl-phenylboronic acid (100 mg, 0.51 mmol, 1.50 equiv) as reactants. Purification via silica gel column (dichloromethane/methanol (15:1)) yielded 60 mg (51%) of 2-phenyl-3-(4-phenyl-phenyl)quinoxaline-6-carboxylic acid as a light yellow solid.

Provenance & Evidence