HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium tert-butoxide → HCID 13351954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | HCID 90388426 | HCID 90388426 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | HCID 13351954 | HCID 13351954 | 84.6% |
Reaction Steps
To a solution of 4,5,6,7-tetrahydro-7-methylene-5-tosylthieno[3,2-c]pyridine (150 mg, 0.491 mmol, 1.0 equiv) in HOt-Bu (5 mL) was added KOt-Bu (110 mg, 0.982 mmol, 2.0 equiv) and heated to reflux for 3 h. Purification by column chromatography using ethyl acetate elution gave 62 mg of the yellow solid, 85%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09370515B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-8b76e2885cd24cc2905e578c53cb89bd |
| Source note | uspto-grants-2016_06 |