HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → 1-(2-(2,3-Dimethylbut-2-en-1-yl)indolin-1-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Indole | HCID 798 | — |
| Reactant | Tin tetrachloride | HCID 24287 | — |
| Reactant | 3H-Indole | HCID 3083560 | — |
| Reactant | 3,3,4-Trimethylpent-4-en-2-one | HCID 13262537 | — |
| Product | 1-(2-(2,3-Dimethylbut-2-en-1-yl)indolin-1-yl)ethanone | HCID 71525879 | 58% |
Reaction Steps
Following the general procedure as described in Example 11, 3,3,4-trimethylpent-4-en-2-one (0.50 g, 3.96 mmol), 1H-indole (0.56 g, 4.75 mmol) which was in situ isomerized to 3H-indole, and SnCl4 (1.24 g, 4.75 mmol) in 1,2-dichloroethane (40 ml) were reacted to give the title product as a white solid (0.56 g, 58%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371262B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-cfeb19e361a74c21b17c8dd50fedbe70 |
| Source note | uspto-grants-2016_06 |