Potassium Hydroxide → HCID 53241517, compound

HRID 2205275Notes

Reaction equation

HRID 2205275 reaction equation
[OH-].[K+].[CH3:3][N:4]([CH3:10])[CH2:5][CH:6]([OH:9])[CH2:7]O.CS([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]/[CH:24]=[CH:25]\[CH2:26]/[CH:27]=[CH:28]\[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])(=O)=O>C1(C)C=CC=CC=1>[CH2:16]([O:15][CH:5]([N:4]([CH3:10])[CH3:3])[CH:6]([O:9][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]/[CH:24]=[CH:25]\[CH2:26]/[CH:27]=[CH:28]\[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH3:7])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]/[CH:24]=[CH:25]\[CH2:26]/[CH:27]=[CH:28]\[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33]

Participants

5

Reactant 3

HCID 14797Potassium HydroxideHCID 790783-(Dimethylamino)-1,2-propanediolHCID 59753235Linoleyl methanesulfonate

Product 1

HCID 53241517HCID 53241517, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In a nitrogen atmosphere, dehydrated toluene (30 ml) and potassium hydroxide (4.9 g, 87.0 mmol) were added to a four-necked flask, and 3-(dimethylamino)-1,2-propanediol (0.57 g, 4.78 mmol: DAP) was dropped under agitation. Thereafter, linoleyl methane sulfonate (5.0 g, 14.5 mmol) was added, and reaction was effected at room temperature for 14.5 hours. The reaction was terminated because isomers increased to 0.079%, although remaining linoleyl methane sulfonate was 51.1% and, therefore, 5.0% or less was not satisfied (degree of conversion: 28.9%, integrated value of isomer: 0.079).

Workup

  1. customreaction
  2. customThe reaction was terminated because isomers
  3. temperatureincreased to 0.079%

Sources & evidence

ORD record
ord-87e5951145924360858f4d16f0a256ce
Source dataset
uspto-grants-2016_06
Patent number
US09371271B2

Reaction notes

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