HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 178453006, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 2-Amino-4-chlorobenzenethiol | HCID 12000 | — |
| Reactant | Di-tert-butyl diazene-1,2-dicarboxylate | HCID 6034084 | — |
| Reactant | HCID 178453005 | HCID 178453005 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178453006 | HCID 178453006 | — |
Reaction Steps
A solution of tert-butyl (5-(hydroxymethyl)-4H-1,2,4-triazol-3-yl)carbamate (190 mg, 0.888 mmol), 2-amino-4-chlorobenzenethiol (213 mg, 1.332 mmol), PPh3 (466 mg, 1.776 mmol) and di-tert-butylazodicarboxylate (409 mg, 1.776 mmol) in CH2Cl2 (10 ml) was stirred at room temperature for 2 days. The solvent was then removed and the crude residues was loaded on silica gel column to get the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371278B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-f1c860961f6c4877b29fa9420d08cdb6 |
| Source note | uspto-grants-2016_06 |