HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → HCID 22324249, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,3-Dimethoxyphenol | HCID 78828 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 22324249 | HCID 22324249 | 46% |
Reaction Steps
To a solution of 2,3-dimethoxyphenol in acetone was added an equimolar amount of 1,2-dibromoethane and excess K2CO3 and heated under reflux overnight. The reaction mixture was filtered and the solvent was evaporated in vacuo. The pure product was obtained with flash chromatography in cyclohexane: EtOAc 5:1 in 46% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371322B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-0693c5762d5c4183b9eba07a02fb786b |
| Source note | uspto-grants-2016_06 |