HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxy-1-(pyrrolidin-1-yl)ethan-1-one → 2-(4-Chloro-3-methyl-5-phenyl-pyrazolo[3,4-c]pyridazin-1-yl)-1-pyrrolidin-1-yl-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxy-1-(pyrrolidin-1-yl)ethan-1-one | HCID 6480485 | — |
| Reactant | CID 86717276 | HCID 86717276 | — |
| Product | 2-(4-Chloro-3-methyl-5-phenyl-pyrazolo[3,4-c]pyridazin-1-yl)-1-pyrrolidin-1-yl-ethanone | HCID 86717278 | — |
Reaction Steps
Compound Iw was synthesized from 4-chloro-3-methyl-5-phenyl-1H-pyrazolo[3,4-c]pyridazine and 2-hydroxy-1-(pyrrolidin-1-yl)ethanone following the general procedure for the Mitsunobu reaction described above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371332B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-11945bfce55247a6adbe0bc1bf76b86c |
| Source note | uspto-grants-2016_06 |