HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Hydroxyethyl)-2-pyrrolidinone → 1-[2-(4-Chloro-3,5-diphenyl-pyrazolo[3,4-c]pyridazin-1-yl)ethyl]pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Hydroxyethyl)-2-pyrrolidinone | HCID 76980 | — |
| Reactant | CID 86697018 | HCID 86697018 | — |
| Product | 1-[2-(4-Chloro-3,5-diphenyl-pyrazolo[3,4-c]pyridazin-1-yl)ethyl]pyrrolidin-2-one | HCID 74221021 | — |
Reaction Steps
Compound IIb was synthesized from 4-chloro-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and 1-(2-hydroxyethyl)pyrrolidin-2-one following the general procedure for the Mitsunobu reaction as described above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371332B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-a793530b8fa3489896e20064be591200 |
| Source note | uspto-grants-2016_06 |