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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2205802Generated: November 1, 2026

3,3,3-Trifluoro-1-propanol → 4-Chloro-3,5-diphenyl-1-(3,3,3-trifluoropropyl)pyrazolo[3,4-c]pyridazine

https://huagongshe.com/reaction/2205802

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3,3-Trifluoro-1-propanolHCID 137512—
ReactantCID 86697018HCID 86697018—
Product4-Chloro-3,5-diphenyl-1-(3,3,3-trifluoropropyl)pyrazolo[3,4-c]pyridazineHCID 74221019—

Reaction Steps

Compound IId was synthesized from 4-chloro-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and 3,3,3-trifluoropropan-1-ol following the general procedure for the Mitsunobu reaction as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09371332B2
Source datasetuspto-grants-2016_06
ORD IDord-06197fca9d484a91a015ac81c607c34f
Source noteuspto-grants-2016_06