4-Hydroxy-2-Butanone → HCID 86717306, compound

HRID 2205811Notes

Reaction equation

[Cl:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:6][N:5]=[C:4]2[NH:14][N:15]=[C:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:3]=12.O[CH2:24][CH2:25][C:26](=[O:28])[CH3:27]>>[Cl:1][C:2]1[C:7]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)=[N:6][N:5]=[C:4]2[N:14]([CH2:24][CH2:25][C:26](=[O:28])[CH3:27])[N:15]=[C:16]([C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:3]=12

Participants

Reactant 2

HCID 1115094-Hydroxy-2-Butanone

HCID 86697018CID 86697018

Product 1

HCID 86717306HCID 86717306, compound

Procedure

Compound IIm was synthesized from 4-chloro-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and 4-hydroxybutan-2-one following the general procedure for the Mitsunobu reaction as described above.

Workup

customfor the Mitsunobu reaction

Sources & evidence

ORD record: ord-0673dffb14f44333bd633fdec2cc7fc9
Source dataset: uspto-grants-2016_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09371332B2

Reaction notes

Loading…