4-(Trifluoromethyl)aniline → HCID 86706292, compound

Participants

Reaction Steps

The title compound was prepared in 63% yield from compound (10) and 4-trifluoromethyl phenylamine using the method described for Preparation 35. 1H-NMR (CDCl3, 500 MHz): δ 1.53 (m, 9H), 1.70 (m, 9H), 6.61 (d, J=0.95 Hz, 1H), 6.81 (br s, 1H), 7.47 (d, J=8.51 Hz, 2H), 7.57 (d, J=8.20 Hz, 2H), 7.73 (m, 1H), 7.83 (d, J=0.63 Hz, 1H), 8.23 (d, J=0.63 Hz, 1H), 8.52 (d, J=0.95 Hz, 1H). 19F-NMR (CDCl3): δ −61.73.

Provenance & Evidence