Ethyl chloroformate → HCID 86706316, compound

HRID 2205926Notes

Reaction equation

HRID 2205926 reaction equation
[Br:1][C:2]1[N:7]=[CH:6][C:5]2[CH:8]=[C:9]([C:11]3[CH:12]=[N:13][N:14]([CH3:16])[CH:15]=3)[NH:10][C:4]=2[CH:3]=1.[CH2:17]([O:19][C:20](Cl)=[O:21])[CH3:18]>>[CH2:17]([O:19][C:20]([N:10]1[C:4]2[CH:3]=[C:2]([Br:1])[N:7]=[CH:6][C:5]=2[CH:8]=[C:9]1[C:11]1[CH:12]=[N:13][N:14]([CH3:16])[CH:15]=1)=[O:21])[CH3:18]

Participants

3

Reactant 2

HCID 10928Ethyl chloroformateHCID 867062766-Bromo-2-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridine

Product 1

HCID 86706316HCID 86706316, compound

Procedure

Prepared according to Preparation 128 using 6-bromo-2-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridine (Preparation 22) and ethylchloroformate. 1H-NMR (500 MHz, CDCl3): δ 1.38 (t, J=7.1 Hz, 3H), 3.95 (s, 3H), 4.45 (q, J=7.1 Hz, 2H), 6.56 (s, 1H), 7.62 (s, 1H), 7.63 (s, 1H), 8.12 (s. 1H), 8.53 (s, 1H).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-89fe31f5d87f4c06b28dcaf0d8cf7976
Source dataset
uspto-grants-2016_06
Patent number
US09371319B2

Reaction notes

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