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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2206121Generated: November 1, 2026

Ethanol → HCID 117987901, compound

https://huagongshe.com/reaction/2206121

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantHCID 117988001HCID 117988001—
CatalystPalladiumHCID 23938—
SolventDimethylformamideHCID 6228—
ProductHCID 117987901HCID 117987901123%

Reaction Steps

A mixture of 4-(4-bromo-3-cyclopentyl-7-methoxy-1H-pyrazolo[3,4-c]pyridin-1-yl)thiophene-2-carboxamide (60 mg) obtained in Step A of Example 67 and 10% palladium/carbon (50% wet, 15 mg) in a mixed solvent of ethanol (10 mL) and DMF (3 mL) was stirred under hydrogen atmosphere at room temperature for 15 hr. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (60 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09371320B2
Source datasetuspto-grants-2016_06
ORD IDord-917caf6bd96648cd9df921cedfeb180f
Source noteuspto-grants-2016_06