HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2206231Generated: October 31, 2026
HCID 117988280, compound → HCID 117988370, compound
https://huagongshe.com/reaction/2206231
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 117988280 | HCID 117988280 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 117988370 | HCID 117988370 | 97.5% |
Reaction Steps
To a solution of 3-(4-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)phenyl)-1-(2,6-difluorophenyl)-4-methoxy-1H-pyrazolo[4,3-c]pyridine (670 mg) in methanol (10 mL) was added 10% palladium carbon (80 mg), and the mixture was stirred overnight at 50° C. under hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated to give the title compound (540 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09371320B2 |
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| Source dataset | uspto-grants-2016_06 |
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| ORD ID | ord-5492e7d5abee4e1b8233966cacf5d29c |
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| Source note | uspto-grants-2016_06 |
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