Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2206231Generated: October 31, 2026

HCID 117988280, compound → HCID 117988370, compound

https://huagongshe.com/reaction/2206231

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 117988280HCID 117988280—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
ProductHCID 117988370HCID 11798837097.5%

Reaction Conditions

Temperature50 °C

Reaction Steps

To a solution of 3-(4-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)phenyl)-1-(2,6-difluorophenyl)-4-methoxy-1H-pyrazolo[4,3-c]pyridine (670 mg) in methanol (10 mL) was added 10% palladium carbon (80 mg), and the mixture was stirred overnight at 50° C. under hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated to give the title compound (540 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09371320B2
Source datasetuspto-grants-2016_06
ORD IDord-5492e7d5abee4e1b8233966cacf5d29c
Source noteuspto-grants-2016_06