Hydrochloric Acid → 2-Nitro-1-[3-(trifluoromethyl)phenyl]ethanamine hydrochloride

Participants

Reaction Steps

Of the compound from Example 12A, 340 mg (1.02 mmol) were admixed at RT with 6.8 ml of a 4N solution of hydrogen chloride in dioxane, and stirred for 1 h. The reaction mixture was concentrated under reduced pressure and dried in an HV. This gave 274 mg (99% of theory) of the title compound.

Provenance & Evidence