Methanol → HCID 19074130, compound
Reaction equation
[CH3:1][OH:2].[CH3:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]>>[CH3:1][OH:2].[CH3:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]Participants
3
Reactant 2
Product 1
Conditions
- Temperature
- 40 °C
Procedure
To the hot solution of Compound 1 (60 g) dissolved in refluxing MeOH (360 mL, at around 64° C.) in a 1 L 3-neck round bottom flask was slowly added n-heptane (360 mL) by maintaining the internal temp above 50° C. (over 40 min). The contents were held at around 55° C. for 30 min before gradually cooling to 40° C. over 6 h period.
Workup
- temperatureby maintaining the internal temp above 50° C. (over 40 min)
Sources & evidence
- ORD record
- ord-113031097d454e5da382c540341cb5bf
- Source dataset
- uspto-grants-2016_06
- Patent number
- US09371344B2
Reaction notes
Loading…