反应详情

Of the compound from Example 100A, 3.87 g (11.2 mmol) were hydrogenated in 230 ml of methanol with 5 ml of Raney nickel suspension (50% in water) at a hydrogen pressure of 3 bar for 3 h. The reaction mixture was filtered over celite and washed with methanol, and the filtrate was freed from the solvent on a rotary evaporator. The residue was dried in an HV. This gave 3.50 g (99% of theory) of the title compound.

1. filtrationThe reaction mixture was filtered over celite
2. washwashed with methanol
3. customthe filtrate was freed from the solvent on a rotary evaporator
4. customThe residue was dried in an HV