HCID 117778770, compound → HCID 117779032, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-methyl-1-(quinolin-5-yl)-1H-indole-3-carboxylic acid (Example 40) (25 mg) in acetic acid (3 mL) was added PtO2 (50 mg) at 22° C. The reaction was stirred at 22° C. under H2 ball for 20 hrs. Then the mixture was filtered and the filtrate was purified by column chromatography on silica gel eluted with dichloromethane:methanol=70:1 to the title compound as a yellow solid (20 mg, 71%).

Provenance & Evidence