HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → HCID 71110576, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 71110548 | HCID 71110548 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 71110576 | HCID 71110576 | 74% |
Reaction Steps
To a suspension of compound 138 (50 mg, 0.09 mmol) in CH3OH (5.0 mL) was added NaOMe (100 μL, 25% solution in CH3OH) at room temperature. After 1 h, the resulting mixture was concentrated in vacuo. The crude was purified by preparative HPLC (reverse phase) to provide the title compound (29 mg, 74%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371303B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-138760bd713d485ca4b534c2052abc55 |
| Source note | uspto-grants-2016_06 |