HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → HCID 71110679, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 71110678 | HCID 71110678 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 71110679 | HCID 71110679 | 42% |
Reaction Steps
To a suspension of compound 143 (40 mg, 0.07 mmol) in CH3OH (5.0 mL) was added NaOMe (100 μL, 25% solution in CH3OH) at room temperature. After 1 h, the resulting mixture was concentrated in vacuo. The crude was purified by preparative HPLC (reverse phase) to provide the title compound (12 mg, 42%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09371303B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-05bdd53cdc8d468c834574c3d66b232c |
| Source note | uspto-grants-2016_06 |