HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbazole → HCID 86723548, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbazole | HCID 6854 | — |
| Reactant | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Reactant | 3-Bromo-5-chlorobenzo[b]thiophene | HCID 14242338 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86723548 | HCID 86723548 | 129.4% |
Reaction Steps
In a 250 mL 2-neck round flask 3-bromo-5-chlorobenzothiophene (2 g, 8.1 mmol), carbazole (0.675 g, 4.05 mmol), CuI (0.46 g, 24.3 mmol), trans-1,2-dicyclohexane-diamine (0.92 g, 2.43 mmol), K3PO4 (3.43 g, 16.2 mmol), and 150 mL of 1,4-dioxane were poured, and refluxed and stirred. After the reaction, the solid matter was filtered. And after the organic solvent was distilled in vacuum and removed, column chromatography (Hex:E.A=9:1) is performed, the solution was distilled in vacuum, giving 1.75 g of white solid (65% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09373794B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-2603fd701a1b46179a1cc521a47b63df |
| Source note | uspto-grants-2016_06 |