Carbazole → HCID 86723549, compound

Participants

Reaction Steps

In a 250 mL 2-neck round flask, 5 mL of tetrahydrofuran (THF) was poured to carbazole (0.75 g, 4.5 mmol). Then, a 2.5Mn-butyllithium/hexane solution (1.8 ml) was gradually added to the mixture in an ice bath. This mixture solution was stirred at room temperature for minutes, and then 9-(5-chlorobenzothiophen-3-yl)carbazole (1.5 g, 4.5 mmol) and tetrakis(triphenylphosphine)palladium(0) (Pd(pph3)4) (0.024 g) were poured to the mixture solution, the resulting mixture was dissolved in and tetrahydrofuran, and reacted at 80° C. After the reaction, the precipitate was filtered and recrystallized with dichloromethane and methanol, thereby giving 1.71 g of a product (82%).

Provenance & Evidence