Thionyl Chloride → 1,1,2,2-Tetrafluoroethanesulfonic acid
Reaction equation
O.[F:2][CH:3]([F:11])[C:4]([F:10])([F:9])[S:5]([OH:8])(=[O:7])=[O:6].S(Cl)(Cl)=O>>[F:2][CH:3]([F:11])[C:4]([F:10])([F:9])[S:5]([OH:8])(=[O:7])=[O:6]Participants
3
Conditions
- Temperature
- 80 °C
Procedure
The tetrafluoroethanesulfonic acid monohydrate (96 g) was taken in a reaction vessel and thionyl chloride (160 g) was added drop-wise at 25° C. over a period of 3 hours. The temperature of reaction mixture was raised to 80° C. and the mixture was refluxed for 30 minutes. The mixture was cooled to 40° C. The crude material (69 g) was subjected to distillation under vacuum.
Workup
- customThe temperature of reaction mixture
- temperaturethe mixture was refluxed for 30 minutes
- temperatureThe mixture was cooled to 40° C
- distillationThe crude material (69 g) was subjected to distillation under vacuum
Sources & evidence
- ORD record
- ord-fc7a942ef0ba4d598f38e0a9145941a7
- Source dataset
- uspto-grants-2016_06
- Patent number
- US09376379B2
Reaction notes
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