HCID 84651427, compound → HCID 89676864, compound

HRID 2207026Notes

Reaction equation

HRID 2207026 reaction equation
[CH3:1][S:2]([O:5][CH2:6][C:7]1[CH:8]=NC=N[CH:12]=1)(=[O:4])=[O:3].[CH:13]1([C:17]2[CH:22]=CC(CO)=C[CH:18]=2)[CH2:16][CH2:15][CH2:14]1>>[CH3:1][S:2]([O:5][CH2:6][C:7]1[CH:8]=[CH:22][C:17]([CH:13]2[CH2:16][CH2:15][CH2:14]2)=[CH:18][CH:12]=1)(=[O:4])=[O:3]

Participants

3

Reactant 2

HCID 84651427HCID 84651427, compoundHCID 86610239Methanesulfonic acid pyrimidin-5-ylmethyl ester

Product 1

HCID 89676864HCID 89676864, compound

Procedure

4-Cyclobutylbenzyl methanesulfonate was prepared in a similar manner as used to prepare pyrimidin-5-ylmethyl methanesulfonate using (4-cyclobutylphenyl)methanol instead of pyrimidin-5-ylmethanol. The product was used directly in the next reaction without characterization.

Workup

  1. customThe product was used directly in the next reaction without characterization

Sources & evidence

ORD record
ord-8295744bb9d44c1bb31c0753d07e9dd9
Source dataset
uspto-grants-2016_06
Patent number
US09376392B2

Reaction notes

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