HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Benzylamino)but-3-en-2-one → N-[3-(3-acetyl-1-benzyl-4H-pyridin-4-yl)propyl]-3,4-dimethoxy-N-phenyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Benzylamino)but-3-en-2-one | HCID 521443 | — |
| Reactant | 3,4-dimethoxy-N-[(E)-6-oxohex-4-enyl]-N-phenyl-benzamide | HCID 118557863 | — |
| Product | N-[3-(3-acetyl-1-benzyl-4H-pyridin-4-yl)propyl]-3,4-dimethoxy-N-phenyl-benzamide | HCID 118558068 | — |
Reaction Steps
The title compound 36 is prepared according to the procedure reported in step D of Example 8 with aldehyde 38 (706 mg, 2 mmol) and enamine 30 (350 mg, 2 mmol) as reactants. (Yield 360 mg, 35%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-70f905771b3e4a419aca3b57ad833124 |
| Source note | uspto-grants-2016_06 |