HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-methoxy-3,4-dihydroisoquinolin-1(2H)-one → 2-But-3-enyl-6-methoxy-3,4-dihydroisoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-methoxy-3,4-dihydroisoquinolin-1(2H)-one | HCID 10607392 | — |
| Reactant | But-3-enyl 4-methylbenzenesulfonate | HCID 11299102 | — |
| Product | 2-But-3-enyl-6-methoxy-3,4-dihydroisoquinolin-1-one | HCID 118558012 | — |
Reaction Steps
The title compound 49 is prepared according to the procedure reported in step B of Example 8 with amide 42 (0.32 g, 1.8 mmol) and but-3-enyl 4-methylbenzenesulfonate (1.63 g, 4 equiv) as reactants. Yellow oil. (Yield 0.29 g, 69%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-f0c70bc622d54a418348e201cf127dc8 |
| Source note | uspto-grants-2016_06 |