HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(benzylamino)but-2-enoate → HCID 118558031, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(benzylamino)but-2-enoate | HCID 70166001 | — |
| Reactant | (E)-4-(6-methoxy-1-oxo-tetralin-2-yl)but-2-enal | HCID 90303875 | — |
| Product | HCID 118558031 | HCID 118558031 | — |
Reaction Steps
The title compound 69 is prepared according to the procedure reported in step D of Example 8 with aldehyde 54 (100 mg, 0.41 mmol) and enamine 70 (90.0 mg, 0.37 mmol) as reactants. Purification by column chromatography on SiO2 (Petroleum Ether/EtOAc=2:1) afford the title compound 69 as a yellow oil. (Yield 80 mg, 45%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-af3332c6bb134c3f87cf2b98e941f48d |
| Source note | uspto-grants-2016_06 |