2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 118557796, compound

Participants

Reaction Steps

To a solution of compound 67 (30.0 mg, 0.064 mmol) in acetonitrile (1 mL) was added DDQ (1 equiv) in one portion at room temperature. After completion of the reaction, acetonitrile was removed under reduced pressure and the residue was taken up in dichloromethane (10 mL). The organic layer was successively washed with aqueous solution of HCl 1M and brine, dried over magnesium sulfate, filtered and concentrated to dryness. The obtained solid was placed in presence of anion exchange resin (Amberlyst Cl−) in acetonitrile for 24 h. After filtration and concentration, the title compound 83 was obtained as a yellow solid (Yield 19.3 mg, 60%).

Provenance & Evidence