HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-alpha-tetralone → (2E)-2-[(3-bromo-4-pyridyl)-methylene]-6-methoxy-tetralin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-alpha-tetralone | HCID 14112 | — |
| Reactant | 3-Bromopyridine-4-carboxaldehyde | HCID 2762997 | — |
| Product | (2E)-2-[(3-bromo-4-pyridyl)-methylene]-6-methoxy-tetralin-1-one | HCID 118557971 | — |
Reaction Steps
The title compound 87 is prepared according to the procedure reported in Example 34.2 with 6-methoxy-1-tetralone (4.74 g, 26.9 mmol) and 3-bromo-4-pyridinecarboxaldehyde (5.0 g, 26.9 mmol) as reactants. White solid. (Yield 7.0 g, 76%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-1c1ba8fd640d41209b90be6f84f6ece8 |
| Source note | uspto-grants-2016_06 |