5,6-Dimethoxy-1-indanone → HCID 118558042, compound

HRID 2207189Notes

Reaction equation

HRID 2207189 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[C:8](=[O:14])[CH2:7][CH2:6]2.[Br:15][C:16]1[CH:17]=[N:18][CH:19]=[CH:20][C:21]=1[CH:22]=O>>[Br:15][C:16]1[CH:17]=[N:18][CH:19]=[CH:20][C:21]=1/[CH:22]=[C:7]1/[C:8](=[O:14])[C:9]2[C:5]([CH2:6]/1)=[CH:4][C:3]([O:2][CH3:1])=[C:11]([O:12][CH3:13])[CH:10]=2

Participants

3

Reactant 2

HCID 750185,6-Dimethoxy-1-indanoneHCID 27629973-Bromopyridine-4-carboxaldehyde

Product 1

HCID 118558042HCID 118558042, compound

Procedure

The title compound 89 is prepared according to the procedure reported in Example 34.1 with 5,6-dimethoxy-1-indanone (1.92 g, 10 mmol) and 3-bromo-4-pyridinecarboxaldehyde (2.3 g, 10 mmol) as reactants. White solid. (Yield 2.34 g, 65%).

Sources & evidence

ORD record
ord-536bb0028e9f47e8bef01e434b04962b
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

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