3-Bromopyridine-4-carboxaldehyde → HCID 118558022, compound

HRID 2207190Notes

Reaction equation

HRID 2207190 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[O:11])[CH2:6][CH2:5]2.[Br:12][C:13]1[CH:14]=[N:15][CH:16]=[CH:17][C:18]=1[CH:19]=O>>[Br:12][C:13]1[CH:14]=[N:15][CH:16]=[CH:17][C:18]=1/[CH:19]=[C:6]1/[C:7](=[O:11])[C:8]2[C:4]([CH2:5]/1)=[CH:3][C:2]([CH3:1])=[CH:10][CH:9]=2

Participants

3

Reactant 2

HCID 27629973-Bromopyridine-4-carboxaldehydeHCID 101300315-METHYL-1-INDANONE

Product 1

HCID 118558022HCID 118558022, compound

Procedure

The title compound 90 is prepared according to the procedure reported in Example 34.1 with 5-methyl-1-indanone (0.73 g, 5 mmol) and 3-bromo-4-pyridinecarboxaldehyde (0.93 g, 5 mmol) as reactants. White solid. (Yield 1.24 g, 79%).

Sources & evidence

ORD record
ord-c411fc75233b4fb98182ca1aafaf0419
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

Loading…