5,6-Dimethyl-1-indanone → HCID 118558028, compound

HRID 2207191Notes

Reaction equation

HRID 2207191 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[CH3:11])[C:7](=[O:12])[CH2:6][CH2:5]2.[Br:13][C:14]1[CH:15]=[N:16][CH:17]=[CH:18][C:19]=1[CH:20]=O>>[Br:13][C:14]1[CH:15]=[N:16][CH:17]=[CH:18][C:19]=1/[CH:20]=[C:6]1/[C:7](=[O:12])[C:8]2[C:4]([CH2:5]/1)=[CH:3][C:2]([CH3:1])=[C:10]([CH3:11])[CH:9]=2

Participants

3

Reactant 2

HCID 278785,6-Dimethyl-1-indanoneHCID 27629973-Bromopyridine-4-carboxaldehyde

Product 1

HCID 118558028HCID 118558028, compound

Procedure

The title compound 92 is prepared according to the procedure reported in Example 35.3 with 5,6-dimethyl-1-indanone (0.40 g, 2.5 mmol) and 3-bromo-4-pyridinecarboxaldehyde (0.45 g, 2.5 mmol) as reactants. Yellow solid. (Yield 0.48 g, 58%).

Sources & evidence

ORD record
ord-b9880b68ff154a7aa877203450590b2b
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

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