5-Chloro-1-indanone → HCID 118557949, compound

HRID 2207192Notes

Reaction equation

HRID 2207192 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[O:11])[CH2:6][CH2:5]2.[Br:12][C:13]1[CH:14]=[N:15][CH:16]=[CH:17][C:18]=1[CH:19]=O>>[Br:12][C:13]1[CH:14]=[N:15][CH:16]=[CH:17][C:18]=1/[CH:19]=[C:6]1/[C:7](=[O:11])[C:8]2[C:4]([CH2:5]/1)=[CH:3][C:2]([Cl:1])=[CH:10][CH:9]=2

Participants

3

Reactant 2

HCID 1425995-Chloro-1-indanoneHCID 27629973-Bromopyridine-4-carboxaldehyde

Product 1

HCID 118557949HCID 118557949, compound

Procedure

The title compound 94 is prepared according to the procedure reported in Example 35.3 with 5-chloro-1-indanone (0.83 g, 5 mmol) and 3-bromo-4-pyridinecarboxaldehyde (0.93 g, 5 mmol) as reactants. White solid. (Yield 0.44 g, 26%).

Sources & evidence

ORD record
ord-68d1ab5dbdb74ce29ee3c174d76daf11
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

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