HCID 118558022, compound → HCID 118557955, compound

Participants

Reaction Steps

Pt/C (5 wt % loading, 125 mg) was added to a stirred solution of the compound 90 (1.24 g, 4 mmol) in EtOH (40 mL) at room temperature. The resulting suspension was stirred for 3 hours under H2 atmosphere (1 atm) then filtered over Celite, rinsed with dichloromethane and concentrated to dryness. The crude residue was purified by column chromatography on SiO2 (gradient of EtOAc in petroleum ether) to afford the title compound 105 as a white solid (Yield 0.75 g, 59%).

Provenance & Evidence