HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-(bromomethyl)-3-nitro- → 2-[[3-Acetyl-1-[(3-nitrophenyl)methyl]pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-(bromomethyl)-3-nitro- | HCID 77568 | — |
| Reactant | 2-[(3-Acetyl-4-pyridyl)methyl]-6-methoxy-tetralin-1-one | HCID 118558014 | — |
| Product | 2-[[3-Acetyl-1-[(3-nitrophenyl)methyl]pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide | HCID 118557929 | — |
Reaction Steps
The title compound 123 is prepared according to the procedure reported in Example 38.1 with compound 103 (62 mg, 0.2 mmol) and 3-nitrobenzyl bromide (73 mg, 0.34 mmol) as reactants. White solid. (Yield 85.1 mg, 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-008b88086ea949679f2ee830cdc4bfa3 |
| Source note | uspto-grants-2016_06 |