o-Xylyl bromide → HCID 118557800, compound

HRID 2207226Notes

Reaction equation

HRID 2207226 reaction equation
[C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([Cl:20])[CH:17]=2)[C:12]1=[O:21])(=[O:3])[CH3:2].[CH3:22][C:23]1[CH:30]=[CH:29][CH:28]=[CH:27][C:24]=1[CH2:25][Br:26]>>[Br-:26].[C:1]([C:4]1[CH:5]=[N+:6]([CH2:22][C:23]2[CH:30]=[CH:29][CH:28]=[CH:27][C:24]=2[CH3:25])[CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([Cl:20])[CH:17]=2)[C:12]1=[O:21])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 6992o-Xylyl bromideHCID 118557934HCID 118557934, compound

Product 1

HCID 118557800HCID 118557800, compound

Procedure

The title compound 136 is prepared according to the procedure reported in Example 38.1 with compound 110 (90 mg, 0.3 mmol) and 2-methylbenzyl bromide (68 μL, 0.51 mmol) as reactants. White solid. (Yield 119.2 mg, 82%).

Sources & evidence

ORD record
ord-b1289d69fdf2491ca01ef66094078360
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

Loading…