o-Xylyl bromide → HCID 131735886, compound

HRID 2207227Notes

Reaction equation

HRID 2207227 reaction equation
[C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([CH3:20])[CH:17]=2)[C:12]1=[O:21])(=[O:3])[CH3:2].[CH3:22][C:23]1[CH:30]=[CH:29][CH:28]=[CH:27][C:24]=1[CH2:25][Br:26]>>[Br-:26].[C:1]([C:4]1[CH:5]=[N+:6]([CH2:22][C:23]2[CH:30]=[CH:29][CH:28]=[CH:27][C:24]=2[CH3:25])[CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([CH3:20])[CH:17]=2)[C:12]1=[O:21])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 6992o-Xylyl bromideHCID 118557861HCID 118557861, compound

Product 1

HCID 131735886HCID 131735886, compound

Procedure

The title compound 137 is prepared according to the procedure reported in Example 38.1 with compound 114 (55.8 mg, 02 mmol) and 2-methylbenzyl bromide (45 μL, 0.34 mmol) as reactants. White solid. (Yield 78.9 mg, 85%).

Sources & evidence

ORD record
ord-b3d4a1ee7d9b4cae8df8bd06e994c4cc
Source dataset
uspto-grants-2016_06
Patent number
US09376387B2

Reaction notes

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