HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyldihydronicotinamide → 2-[[3-acetyl-1-(p-tolylmethyl)-4H-pyridin-4-yl]methyl]-6-methoxy-tetralin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyldihydronicotinamide | HCID 95276 | — |
| Reactant | 2-[[3-Acetyl-1-(p-tolylmethyl)pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide | HCID 118558069 | — |
| Product | 2-[[3-acetyl-1-(p-tolylmethyl)-4H-pyridin-4-yl]methyl]-6-methoxy-tetralin-1-one | HCID 118557943 | — |
Reaction Steps
The title compound 154 is prepared according to the procedure reported in Example 39.1 with compound 130 (75 mg, 0.154 mmol) and BNAH (33 mg, 1 equiv) as reactants. Yellow solid. (Yield 32.9 mg, 51%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09376387B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-f8007bb87fc64e0fbf7ab50044e2aab8 |
| Source note | uspto-grants-2016_06 |