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HRID220792

反应详情

EQUATION

反应方程式

HRID 220792 的结构方程式

REACTANTS

反应物

2
结构：C1COCCO1.Cl
HCID20443148

1,4-Dioxane hydrochloride

C4H9ClO2

结构：Cn1ncc2c1Nc1cc(Cl)ccc1N(C(=O)C1CCC(CNC(=O)OC(C)(C)C)CC1)C2
HCID136128395

未命名化合物

PRODUCTS

生成物

1
结构：Cl.Cn1ncc2c1Nc1cc(Cl)ccc1N(C(=O)C1CCC(CN)CC1)C2
HCID135736042

未命名化合物

收率 100%

PROCEDURE

实验过程

A solution of [4-(6-chloro-3-methyl-4,10-dihydro-3H-2,3,4,9-tetraaza-benzo[f]azulene-9-carbonyl)-cyclohexylmethyl]-carbamic acid tert-butyl ester from Example E10.1 (775 mg, 1.63 mmol) was reacted with 4N HCl/dioxan using an analogous procedure to that described for Example E4.2 to yield the title compound (655 mg, 100%).