Trifluoroacetic acid → HCID 118432027, compound

Participants

Reaction Steps

5-[3-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-phenyl]-1-(2,4-difluoro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (800.0 mg, 1.32 mmol) prepared in Example 60 and trifluoroacetic acid (1011.0 uL, 13.21 mmol) were added at 0° C. to dichloromethane (6.6 mL). The reaction mixture was stirred at room temperature for 3 hours and then concentrated under reduced pressure to give 820.0 mg of the titled compound as a yellow liquid.

Provenance & Evidence