Trifluoroacetic acid → HCID 118431767, compound

Participants

Reaction Steps

5-[3-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-phenyl]-1-(2-chloro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (1.0 g, 1.8 mmol) prepared in Example 116 and trifluoroacetic acid (1.4 mL, 18.0 mmol) were added at 0° C. to dichloromethane (9.0 mL). The reaction mixture was stirred at room temperature for 1 hour and then concentrated under reduced pressure to give 1.1 g of the titled compound as a yellow liquid.

Provenance & Evidence