Hydrochloric Acid → HCID 118431952, compound

Participants

Reaction Steps

5-[3-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-pyridin-5-yl]-1-(2,4-difluoro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (330.0 mg, 0.6 mmol) prepared in Example 164 was added to a saturated solution of hydrochloric acid in ethyl acetate (2.0 mL). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure to give 310.0 mg of the titled compound as a brown liquid.

Provenance & Evidence