Hydrochloric Acid → HCID 118431721, compound

Participants

Reaction Steps

5-[4-(4-BOC-piperazin-1-yl)-pyridin-2-yl]-1-(2,4-difluoro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (350.0 mg, 0.6 mmol) prepared in Example 181 was added to a saturated solution of hydrochloric acid in ethyl acetate (3.0 mL). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure to give 325.0 mg of the titled compound as a brown liquid.

Provenance & Evidence