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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220802Generated: October 29, 2026

Ethyl 4-piperidinecarboxylate → 1-(Cyclopropylmethyl)piperidine-4-carboxylic acid

https://huagongshe.com/reaction/220802

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-piperidinecarboxylateHCID 70770—
ReactantCyclopropanecarboxaldehydeHCID 123114—
Product1-(Cyclopropylmethyl)piperidine-4-carboxylic acidHCID 16244015—

Reaction Steps

The title compound was prepared from cyclopropanecarboxaldehyde and ethyl isonipecotate using similar procedures to those described for Example E15.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202858B2
Source datasetuspto-grants-2012_06
ORD IDord-946adcaae1bb44ad9d302b3c1b6a754a
Source noteuspto-grants-2012_06