Hydrochloric Acid → HCID 118431739, compound

Participants

Reaction Steps

5-[2-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-pyridin-4-yl]-1-(2,4-difluoro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (350.0 mg, 4.2 mmol) prepared in Example 187 was added to a saturated solution of hydrochloric acid in ethyl acetate (10.0 mL). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure to give 300.0 mg of the titled compound as a brown liquid.

Provenance & Evidence