Hydrochloric Acid → HCID 118431853, compound

Participants

Reaction Steps

1-[3-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-phenyl]-5-(2,4-difluoro-phenyl)-3-pentafluoroethyl-4,5-dihydro-1H-pyrazole (300.0 mg, 0.54 mmol) prepared in Example 205 was added to a saturated solution of hydrochloric acid in ethyl acetate (3.0 mL). The reaction mixture was stirred at room temperature for 2 hours and then concentrated under reduced pressure to give 260.0 mg of the titled compound as a white solid.

Provenance & Evidence