Trifluoroacetic acid → HCID 118431833, compound

Participants

Reaction Steps

1-(2-Chloro-phenyl)-5-[4-(1-BOC-1,2,3,6-tetrahydropyridin-4-yl)-phenyl]-3-[di-(trifluoromethyl)-hydroxy-methyl]-4,5-dihydro-1H-pyrazole (350.0 mg, 0.58 mmol) prepared in Example 291 and trifluoroacetic acid (444.0 uL, 5.79 mmol) were added at 0° C. to dichloromethane (5.0 mL). The reaction mixture was stirred at room temperature for 3 hours and then concentrated under reduced pressure to give 400.0 mg of the titled compound as a yellow liquid.

Provenance & Evidence